7 doctors weighed in:

Gallbladder cancer with severe lung metastasis 4th stage, does chemotherapy work?

7 doctors weighed in
Dr. Andrew Turrisi
Radiation Oncology
4 doctors agree

In brief: GB cancer is

Uncommon, so few studies done prospectively.
Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost.

In brief: GB cancer is

Uncommon, so few studies done prospectively.
Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
1 comment
Dr. Sewa Legha
There is one Prospective randomized trial(NEJM, April 2010) which showed significant improvement in Survival with a combination chemotherapy regimen of Gemcitabine+Cisplatin. It is an option which could be exercised.
Dr. Sewa Legha
Internal Medicine - Oncology
1 doctor agrees

In brief: It is worth a trial

Being a rare cancer, we have limited data about efficacy of chemotherapy.
Yet many phase 2 studies have been done which predictably show that gemcitabine is an active drug and benefits about1/3 patients. More recently combination chemotherapy using Cisplatin with gemcitabine , for the first time, showed a superior efficacy with 2 drugs over one . You have nothing to lose yet may buy 6 to 12 months.

In brief: It is worth a trial

Being a rare cancer, we have limited data about efficacy of chemotherapy.
Yet many phase 2 studies have been done which predictably show that gemcitabine is an active drug and benefits about1/3 patients. More recently combination chemotherapy using Cisplatin with gemcitabine , for the first time, showed a superior efficacy with 2 drugs over one . You have nothing to lose yet may buy 6 to 12 months.
Dr. Sewa Legha
Dr. Sewa Legha
Thank
Get help from a real doctor now
Dr. Crystal Twynham
Board Certified, Surgery
30 years in practice
939K people helped
Continue
111,000 doctors available
Read more answers from doctors