Even DBS surgery!!
Deep brain stimulation
therapy of the stn (sub-thalamic nucleus) or gpi (globus pallidus interna) can greatly improve "on" time (good function with minimized symptoms) & greatly reduce dyskinesia
(twisting, writhing, jerking movements during "on" time).
Good candidates must be not demented, psychiatrically stable, & still demonstrating good symptom relief from meds, but with inconsistent results.