Is hydro citric acid & citrate lyase harmful with one kidney?

Effects on kidney. Citrate lyase is not harmful. The hydroxycitric acid (hydrocitric acid) in small amounts would not be harmful either. Large doses of hydroxycitric acid over time could potentially be harmful although there are no case reports or data to prove this. More important than having one kidney is knowing the kidney function is. Best answered with egfr a calculation of kidney function done by your doctor.