What is the best contraception while on accutane?

The one that... ...Prevents you from getting pregnant. I'm not being flippant; if you get pregnant while taking Accutane the risk of having a baby with birth defects is very high. So you need to do whatever you have to do to avoid becoming pregnant. Most experts advise using at least two distinct forms of birth control. Of course, the only foolproof way to avoid becoming pregnant is to not have sex.