30 doctors weighed in:
What is your opinion on taking st.John's wort?
30 doctors weighed in

Dr. Shariq Refai
Psychiatry
11 doctors agree
In brief: Mild
For mild depression it has shown some benefit.
For moderate to severe not so much.

In brief: Mild
For mild depression it has shown some benefit.
For moderate to severe not so much.
Dr. Shariq Refai
Dr. Shariq Refai
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1 comment
Dr. Alan Ali
Also, SAMe might be worth try, if ok with your doc.
Dr. Heidi Fowler
Psychiatry
7 doctors agree
In brief: Depression
"A 2009 systematic review of 29 international studies suggested that St.
John’s wort may be better than a placebo (an inactive substance that appears identical to the study substance) and as effective as standard prescription antidepressants for major depression of mild to moderate severity." REF: https://nccih.nih.gov/health/stjohnswort/sjw-and-depression.htm. However, many studies are from

In brief: Depression
"A 2009 systematic review of 29 international studies suggested that St.
John’s wort may be better than a placebo (an inactive substance that appears identical to the study substance) and as effective as standard prescription antidepressants for major depression of mild to moderate severity." REF: https://nccih.nih.gov/health/stjohnswort/sjw-and-depression.htm. However, many studies are from
Dr. Heidi Fowler
Dr. Heidi Fowler
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Dr. Alan Ali
Psychiatry
7 doctors agree
In brief: St. John
Fairly decent alternative to antidepressants if patient chooses not to take the other medications.
Same for same. However, these are more expensive & should not be combined with the others.

In brief: St. John
Fairly decent alternative to antidepressants if patient chooses not to take the other medications.
Same for same. However, these are more expensive & should not be combined with the others.
Dr. Alan Ali
Dr. Alan Ali
Thank
5 doctors agree
In brief: Cannot monitor
It can be very effective for some individuals and has been used in europe for a long time for depression.
In us it is not monitored, so you cannot know if you get the correct part of the plant or concentration desired for treatment. So, you cannot rely on consistent efficacy. It interacts with other meds. It is as risky as an ssri. Careful!

In brief: Cannot monitor
It can be very effective for some individuals and has been used in europe for a long time for depression.
In us it is not monitored, so you cannot know if you get the correct part of the plant or concentration desired for treatment. So, you cannot rely on consistent efficacy. It interacts with other meds. It is as risky as an ssri. Careful!
Dr. Caroline Cribari
Dr. Caroline Cribari
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2 comments
Dr. Alan Ali
Risky if taken at same time with SSRIs.
Dr. Pamela Pappas
Use of standardized preparations allows ability to monitor. A good resource to check on particular products is www.consumerlab.com. This by no means includes all that are available, but it's a start.
4 doctors agree
In brief: Mild depression
Not very effective in forms of severe depression.
However , it may be effective in mild forms of depressions or adjustment disorders.

In brief: Mild depression
Not very effective in forms of severe depression.
However , it may be effective in mild forms of depressions or adjustment disorders.
Dr. Marcello Maviglia
Dr. Marcello Maviglia
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Dr. Ahmad M Hadied
Orthopedic Surgery
2 doctors agree
In brief: They say it help
Especially in europe, they use for the treatment of depression.

In brief: They say it help
Especially in europe, they use for the treatment of depression.
Dr. Ahmad M Hadied
Dr. Ahmad M Hadied
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Dr. Ed Friedlander
Pathology
1 doctor agrees
In brief: Seems quite good
Different studies have given different results.
You'll need to find the right dose for yourself. Remember it can cause paresthesias and is a photosensitizer.

In brief: Seems quite good
Different studies have given different results.
You'll need to find the right dose for yourself. Remember it can cause paresthesias and is a photosensitizer.
Dr. Ed Friedlander
Dr. Ed Friedlander
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