7 doctors weighed in:

What are the differences between Prozac and cymbalta (duloxetine)?

7 doctors weighed in
Dr. Austina Cho
Psychiatry
5 doctors agree

In brief: Prozac (fluoxetine) lasts longer

Prozac primarily blocks serotonin reuptake.
Cymbalta (duloxetine) blocks norepinephrine & serotonin reuptake. Prozac lasts up to 2 wks in your system after the last dose. Cymbalta (duloxetine) also is used to treat pain & depression. Prozac can help for some anxiety disorders, bulimia & depression. It has variable efficacy in borderline personality disorder.

In brief: Prozac (fluoxetine) lasts longer

Prozac primarily blocks serotonin reuptake.
Cymbalta (duloxetine) blocks norepinephrine & serotonin reuptake. Prozac lasts up to 2 wks in your system after the last dose. Cymbalta (duloxetine) also is used to treat pain & depression. Prozac can help for some anxiety disorders, bulimia & depression. It has variable efficacy in borderline personality disorder.
Dr. Austina Cho
Dr. Austina Cho
Thank
Dr. Walter Root
Psychiatry
3 doctors agree

In brief: Norepeniphrine

Prozac increases only serotonin while Cymbalta (duloxetine) increase both serotonin and norepinephrine.
Never quit Cymbalta (duloxetine) suddenly or you could feel really lousy...

In brief: Norepeniphrine

Prozac increases only serotonin while Cymbalta (duloxetine) increase both serotonin and norepinephrine.
Never quit Cymbalta (duloxetine) suddenly or you could feel really lousy...
Dr. Walter Root
Dr. Walter Root
Thank
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