I have lupus. Is it safe for me to become pregnant?

High risk. Patients with lupus should be followed by an obstetrician who cares for high risk pregnant patients. It is possible to deliver a normal, healthy baby. Make sure you get good prenatal care and testing. Your blood pressure and urine should be checked periodically.
In most cases...yes. Payton, while just a short while ago, most physicians would have advised against it, today it can be accomplished quite commonly. Your current health status and disease status should be evaluated prior to getting pregnant. Many medications are ill-advised or even deadly for the fetus, so you need to consult your family medicine doctor or obstetrician (ob/gyn) even before attempting pregnancy.