Is multiple sclerosis progressive and fatal?

Prog.disease. There is a variant form of MS that is very aggressive that can lead to coma or death. However most of the other forms do not have such a grave prognosis. If left untreated >30 % of patients will develop significant disability within 20->25 years after onset. Life expectancy is shortened only slightly, death usually results from secondary complications.
Possible, but. If treated aggressively with newer drugs such as Tysabri (natalizumab) or Gilenya, may well have normal lifespan. The primary and secondary progressive forms, however, are tougher to treat, and may acquire secondary infections. The DMT's used, can help prevent progression and disability. The main variation which is dangerous, is the Marburg form, an aggressive serious variation of childhood MS.

Related Questions

A friend of mine was recently diagnosed with primary progressive multiple sclerosis. Is this a fatal disease?

Cannot predict. Primary progressive ms is typically without rapid relapses, but also, without remission. Does not seem to respond well to meds employed in relapsing/remitting form. Most active therapy is symptomatic. However, research is ongoing with Gilenya (fingolimod) for ppms. Other drugs not yet on the market are being studied. Best bet is to get into one of these studies. Contact local medical school. Stay positive. Read more...

Is multiple sclerosis fatal?

Not usually. Ms is a chronic neurological condition, characterized by episodes of neurological disability of variable severity and recovery. A minority of inidividuals can have a very aggressive course, and become so disabled that they are at risk of secondary medical complications which may be fatal. There are subtypes of MS which are so aggressive that a fatal outcome can happen. Fortunately these are rare. Read more...
Most. As short as it sounds...We all die from something. It would be more common than not for people with ms to die from complications resulting from having ms...Whether the inability to have healthy levels of activity lead to weight/cardiovascular issues, or whether due to recurrent utis/immobility causing pneumonia/ulcer issues in more advanced cases, there is slight shorter life expectancy. Read more...
Mostly not so. Studies on pts taking disease modifying agents suggest that normal life span is possible, but if no treatment, life is shortened between 7-14 yrs. There is a deadly form, called Marburg, which is an aggressive downhill course in children, but is quite rare. Read more...

Is primary progessive multiple sclerosis always fatal?

Not necessarily . Ms has been said to shorten life span, and untreated this is correct, but several studies have supported normal life if appropriate potent meds are employed. Primary progressive ms does not respond well to the usual meds, and mostly symptomatic interventions are used. There are many research projects nowadays, and best to contact a medical school and get involved. Read more...