4 doctors weighed in:
If I have the double gene mutation (homozygous) for hemochromatosis but am not clinically iron overloaded (have high iron levels on lab results) at this time, can I develop iron overload later, such as in 2, 5, or 10 or more years later?
4 doctors weighed in

Dr. Gregg Albers
Addiction Medicine
2 doctors agree
In brief: Hemachromatosis
The single gene carrier will likely not develop any symptoms or problems from increased iron absorption.
You will still need to have regular blood work to check for increased iron, and not use any supplements with iron. If you have two genes, your chance is good that you will have high levels of iron, and possibly get damage from the extra iron. Timing is unknown, too many variables.

In brief: Hemachromatosis
The single gene carrier will likely not develop any symptoms or problems from increased iron absorption.
You will still need to have regular blood work to check for increased iron, and not use any supplements with iron. If you have two genes, your chance is good that you will have high levels of iron, and possibly get damage from the extra iron. Timing is unknown, too many variables.
Dr. Gregg Albers
Dr. Gregg Albers
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Dr. Michael Dugan
Internal Medicine - Hematology
In brief: Yes
The onset varies based on other factors, especially sex.
Females are relatively protected until the menopause due to monthly blood loss. Other factors can also be managed. Talk to your doc.

In brief: Yes
The onset varies based on other factors, especially sex.
Females are relatively protected until the menopause due to monthly blood loss. Other factors can also be managed. Talk to your doc.
Dr. Michael Dugan
Dr. Michael Dugan
Thank
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