Does afrin nasal spray work as good as nasonex (mometasone)?

Apples & oranges. Afrin works to reduce blood flow to nasals tissue, leading to reduced swelling. It is used to treat congestion from colds, allergies, etc. Nasonex (mometasone) prevents only symptoms of allergy, such as congestion, but also sneezing, itching, and drainage. Both are very effective, but used for different indications. Use afrin for only a few days at a time, as your nose may literally get addicted to it.