2 doctors weighed in:

Can you take loratadine and zyrtec and Benadryl (diphenhydramine) ?

2 doctors weighed in
Dr. Jack Mutnick
Internal Medicine - Allergy & Immunology

In brief: With Caution

Please see my previous answer to this exact same question.

In brief: With Caution

Please see my previous answer to this exact same question.
Thank
Dr. Alvin Lin
Internal Medicine - Geriatrics

In brief: Don't take together

All 3 drugs mentioned are antihistamines available w/o prescription.
Benadryl (diphenhydramine) is most potent but also most laden w/anticholinergic side effects, eg sedation, dry eyes/mouth, constipation, urinary retention etc. Zyrtec (cetirizine) is more sedating than Claritin (loratadine). Both have less potential side effects than Benadryl but need to find best for you. Don't take together.

In brief: Don't take together

All 3 drugs mentioned are antihistamines available w/o prescription.
Benadryl (diphenhydramine) is most potent but also most laden w/anticholinergic side effects, eg sedation, dry eyes/mouth, constipation, urinary retention etc. Zyrtec (cetirizine) is more sedating than Claritin (loratadine). Both have less potential side effects than Benadryl but need to find best for you. Don't take together.
Thank
Get help from a real doctor now
Dr. Keegan Duchicela
Board Certified,
13 years in practice
16M people helped
Continue
100,000 doctors available