Is abreva and denavir (penciclovir) the same?

Different. While they are both topical treatments for cold sores (herpes simplex), they are different medications. They both may shorten the duration of an active cold sore outbreak somewhat, but through different mechanisms. Abreva has an advantage in that it is available without a prescription.

Related Questions

Which is better abreva or denavir (penciclovir)?

HSV. Abreva is otc and am not at all impressed with its utility. Denavir (penciclovir) requires a prescription. Quite frankly the effect that any topical anti-herpes medication has on a relapse of HSV is minimal at best. Read more...