Is chromium picolinate effective with children with autism?

No scientific basis. There are anecdotal reports of it improving symptoms of autism but there are no appropiriately controlled scientific studies to support its use.
Autism,Herbs. Chromium picolinate is promoted as a nutrtional supplement. It's benefit in 'atypical depression', Insulin resitance in diabetics has failed to show any benefit comparing to a placebo(sugar pill) ! in high doses it caused bone defects in mice. I do not know if any one has studied it for the "treatment' of autism. There is no cure for autism. Early intervention with ot, st and medicine will help.