11 doctors weighed in:
Do antidepressants cause restless legs syndrome?
11 doctors weighed in

Dr. Byron Law-Yone
Psychiatry
6 doctors agree
In brief: Meds can trigger RLS
What "causes" RLS is uncertain.
It may be related to genetics, deficiency of iron in the brain, hormonal changes, pregnancy, parkinson's disease. Medications like antidepressants, antipsychotics, cold and allergy medications can trigger or aggravate rls. Treatment with medication can help diminish symptoms.

In brief: Meds can trigger RLS
What "causes" RLS is uncertain.
It may be related to genetics, deficiency of iron in the brain, hormonal changes, pregnancy, parkinson's disease. Medications like antidepressants, antipsychotics, cold and allergy medications can trigger or aggravate rls. Treatment with medication can help diminish symptoms.
Dr. Byron Law-Yone
Dr. Byron Law-Yone
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Dr. Parham Gharagozlou
Internal Medicine - Sleep Medicine
2 doctors agree
In brief: YES
If somebody has a mild RLS antidepressants like ssri Prozac zoloft (sertraline) Celexa etc.
Can make it worse to the level that patient feels symptoms. It can be significant in fact.

In brief: YES
If somebody has a mild RLS antidepressants like ssri Prozac zoloft (sertraline) Celexa etc.
Can make it worse to the level that patient feels symptoms. It can be significant in fact.
Dr. Parham Gharagozlou
Dr. Parham Gharagozlou
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Dr. Kevin Passer
Pediatrics - Psychiatry
2 doctors agree
In brief: Possibly. Could help
Ssris, if stopped abruptly can cause shock like symptoms which could mimic restless legs.
Buproprion is an antidepressant which effects brain Dopamine and which may help rls. For RLS caused by nightmares, i often prescribe low dose nortriptyline to lessen the vivid dreams.

In brief: Possibly. Could help
Ssris, if stopped abruptly can cause shock like symptoms which could mimic restless legs.
Buproprion is an antidepressant which effects brain Dopamine and which may help rls. For RLS caused by nightmares, i often prescribe low dose nortriptyline to lessen the vivid dreams.
Dr. Kevin Passer
Dr. Kevin Passer
Thank
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