Are there any sexual side effects of zoloft (sertraline)?

Often. For all of the ssris, including zoloft, (sertraline) sexual dysfunction are common side effects. In men this is typically decreased libido and delayed ejaculation, while in women it tends to be decreased libido. Of note, people who are depressed often have reduced libido to begin with.
Zoloft (sertraline) Like other ssris, u can have difficulty with sexual arousal, or difficulty achieving orgasm. Genital anesthesias & decreased response to sexual stimuli are also possible.