What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma (transitional)?
Location. What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma.
Skin cancer. An inverted papilloma is a kind of skin tumor in which the abnormal epithelium grows down and in instead of out on the surface. Dysplasia means some of the growth has abnormal features, on the way toward but not all the way to cancer. Squamous cell carcinoma in situ means the dysplasia is severe, and is essentially cancer confined to the epithelium. Invasive carcinoma is full-blown cancer.
What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?
Premalignant. An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. Read more...