7 doctors weighed in:

What is osteonecrosis of the jaw?

7 doctors weighed in
Dr. William Banks Hinshaw
Obstetrics & Gynecology
2 doctors agree

In brief: A drug side-effect

The drugs for osteoporosis and metastatic bone cancer called bisphosphonates (includes fosamax, actonel, boniva, reclast, (zoledronic acid) zometa, aredia) are associated with a side-effect where part of the bone of the jaw dies, the gum sloughs off, and bone shows where the gum was lost.
It is treatable but not always curable. It has also been found with bevicizumab, an anti-cancer drug, and after jaw radiation.

In brief: A drug side-effect

The drugs for osteoporosis and metastatic bone cancer called bisphosphonates (includes fosamax, actonel, boniva, reclast, (zoledronic acid) zometa, aredia) are associated with a side-effect where part of the bone of the jaw dies, the gum sloughs off, and bone shows where the gum was lost.
It is treatable but not always curable. It has also been found with bevicizumab, an anti-cancer drug, and after jaw radiation.
Dr. William Banks Hinshaw
Dr. William Banks Hinshaw
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Dr. Louis Gallia
Surgery - Oral & Maxillofacial
1 doctor agrees

In brief: Dead bone

Dead bone in jaw.
Usually due to radiation treatment to jaw for cancer. or bone building medications. Serious problem. See oral surgeon for exam/diagnosis/treatment.

In brief: Dead bone

Dead bone in jaw.
Usually due to radiation treatment to jaw for cancer. or bone building medications. Serious problem. See oral surgeon for exam/diagnosis/treatment.
Dr. Louis Gallia
Dr. Louis Gallia
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Dr. David Schleimer
Dentistry - Orthodontics
1 doctor agrees

In brief: Tissue death

Dr. Hinshaw's answer is quite correct regarding osteonecrosis secondary to medication.
It is important to know that osteonecrosis is not confined to the jaw, but rather any bone that continues to lose blood supply and vitality. Certain bacteria are implicated as well. Cutting away dead tissue is a must, and sometimes a patient needs to be put in a hyperbaric chamber (high pressure oxygen). Serious.

In brief: Tissue death

Dr. Hinshaw's answer is quite correct regarding osteonecrosis secondary to medication.
It is important to know that osteonecrosis is not confined to the jaw, but rather any bone that continues to lose blood supply and vitality. Certain bacteria are implicated as well. Cutting away dead tissue is a must, and sometimes a patient needs to be put in a hyperbaric chamber (high pressure oxygen). Serious.
Dr. David Schleimer
Dr. David Schleimer
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1 comment
Dr. David Schleimer
I realize that the question regarded the jaw, but felt the need to clarify that it can happen to all bone (connective tissue).
Dr. Rhett Griggs
Surgery - Hand Surgery
1 doctor agrees

In brief: The

Mandible starts to die for various reasons to cause no blood flow.

In brief: The

Mandible starts to die for various reasons to cause no blood flow.
Dr. Rhett Griggs
Dr. Rhett Griggs
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Dr. Lakhminder Sandhu
General Practice

In brief: Osteonecrosis jaw

Osteonecrosis of the jaw, commonly called ONJ, occurs when the jaw bone is exposed and begins to starve from a lack of blood.
http://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Osteonecrosis-of-the-Jaw-ONJ

In brief: Osteonecrosis jaw

Osteonecrosis of the jaw, commonly called ONJ, occurs when the jaw bone is exposed and begins to starve from a lack of blood.
http://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Osteonecrosis-of-the-Jaw-ONJ
Dr. Lakhminder Sandhu
Dr. Lakhminder Sandhu
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