15 doctors weighed in:

Why do some people get hemolytic uremic syndrome and others don't?

15 doctors weighed in
Dr. James Ferguson
Pediatrics
8 doctors agree

In brief: Immune system quirks

The same reason only 1/200 people with untreated strep A get rheumatic fever or only 5% of those who were infected by poliovirus developed paralysis.
When the bodies immune system creates antibodies to an invading germ, that antibody sometimes gets confused and attacks human tissues as well. There are some human tissue patterns that are more susceptible than others but we can't predict it

In brief: Immune system quirks

The same reason only 1/200 people with untreated strep A get rheumatic fever or only 5% of those who were infected by poliovirus developed paralysis.
When the bodies immune system creates antibodies to an invading germ, that antibody sometimes gets confused and attacks human tissues as well. There are some human tissue patterns that are more susceptible than others but we can't predict it
Dr. James Ferguson
Dr. James Ferguson
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Dr. John Leander Po
Internal Medicine - Infectious Disease
3 doctors agree

In brief: EHEC with STX

Hemoyltic uremic syndrome (hus) is associated with infections involving entero-hemorrhagic e coli (ehec).
This results in bloody diarrhea and hus since this bacteria produces a special group of toxins (verotoxin or shiga toxins- aka stx). The most representative strain of this type of e coli is referred to as o157:h7, responsible for several deadly outbreaks in recent years around the world.

In brief: EHEC with STX

Hemoyltic uremic syndrome (hus) is associated with infections involving entero-hemorrhagic e coli (ehec).
This results in bloody diarrhea and hus since this bacteria produces a special group of toxins (verotoxin or shiga toxins- aka stx). The most representative strain of this type of e coli is referred to as o157:h7, responsible for several deadly outbreaks in recent years around the world.
Dr. John Leander Po
Dr. John Leander Po
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Dr. Quresh Khairullah
Internal Medicine - Nephrology & Dialysis
1 doctor agrees

In brief: See below

Hus is a serious disease, some causes are genetic, some due to certain bacterial products in meat, like e colii infected hamburgers or raw meat patients can develop severe anemia and kidney failure so not everyone gets it.

In brief: See below

Hus is a serious disease, some causes are genetic, some due to certain bacterial products in meat, like e colii infected hamburgers or raw meat patients can develop severe anemia and kidney failure so not everyone gets it.
Dr. Quresh Khairullah
Dr. Quresh Khairullah
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Dr. Larry Lutwick
Internal Medicine - Infectious Disease

In brief: Certain risks

Include younger children, elevated initial white blood cell count and, especially the use of antibiotics early in the illness with enterohemorrhagic e .
Coli strains.

In brief: Certain risks

Include younger children, elevated initial white blood cell count and, especially the use of antibiotics early in the illness with enterohemorrhagic e .
Coli strains.
Dr. Larry Lutwick
Dr. Larry Lutwick
Thank
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