Red bump on pinky squeezed it and blood blister popped up now I'm feeling sick?

Rash. Doubt you're feeling sick from the lesion on your pinky as it is limited to that area and less likely to give you systemic reaction. The lesion needs to be looked at either by having a local doc do so or sending us a picture.

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Red painful raised bump on hand. Slowly growing looks like blood blister but feels like splinter in it. Suddenly appeared?

Infection Likely. I would make sure to have this evaluated by your doctor. Given your medical history and the medications you are taking (Humira), you might have a skin infection that will require doctor-directed care. Your immune system is suppressed due to the Humira, (adalimumab) so you are more at risk for getting skin infections. Get it checked out. Read more...