What can I do to not get fluid accumulation in the skin?

Lower leg swelling. One of the most common forms of 'water in the skin' is edema or swelling of the lower legs. It's common during pregnancy and is frequently related to poor circulation and heart failure as a person gets older. Support stockings are usually the best way to treat this problem. Exercise can also help. Sometimes salt intake is a factor too.
Huh? To be honest, I have no idea what you are talking about. Do you mean blisters? Swelling? What? There is no way we can tell you how to avoid this problem without some clue as to what might be causing it.