Maybe I worry too much, but I want to know how joint sprain will affect my overall health.?

Sprain. First a sprain is an injury to a ligament. Sprains can be as simple as stretching a ligament to completely tearing the ligament. An iniital sprained ligament should be treated with rice. Once swelling resolves the joint may need some rehab consisting of exercises to strengthen the joint. If a joint is weak you are more susceptible to further injury.