2 doctors weighed in:

What if someone has anaphylaxis and they are allergic to epinephrine? Also, is it possible to be epinephrine resistant?

2 doctors weighed in
Dr. John Chiu
Internal Medicine - Allergy & Immunology

In brief: Not possible

I know of no one who is allergic to Epinephrine even though you may get shaking or rapid heart beats from it.
However i would take the side effects anytime if I have an anaphylactic reaction. If the anaphylaxis is severe and the treatment is delayed, you may not respond to Epinephrine alone and IV fluid may well be needed.

In brief: Not possible

I know of no one who is allergic to Epinephrine even though you may get shaking or rapid heart beats from it.
However i would take the side effects anytime if I have an anaphylactic reaction. If the anaphylaxis is severe and the treatment is delayed, you may not respond to Epinephrine alone and IV fluid may well be needed.
Dr. John Chiu
Dr. John Chiu
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Dr. Ankush Bansal
Internal Medicine

In brief: Impossible

You cannot be allergic to epinephrine.
That is impossible. Your body makes Epinephrine naturally and it is necessary to survive. You cannot be Epinephrine resistant. When you are given a shot of epinephrine, it last between 2 and 5 minutes max. So, it will wear off. The point in anaphylaxis is to stop the allergic cascade that happens.

In brief: Impossible

You cannot be allergic to epinephrine.
That is impossible. Your body makes Epinephrine naturally and it is necessary to survive. You cannot be Epinephrine resistant. When you are given a shot of epinephrine, it last between 2 and 5 minutes max. So, it will wear off. The point in anaphylaxis is to stop the allergic cascade that happens.
Dr. Ankush Bansal
Dr. Ankush Bansal
Thank
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