Is it still possible to get blood clots (dvt, pe) while on warfarin? Have factor v leiden. Suffered DVT and pe 18 months ago. Inr 2.5 last check.

Warfarin failures. Warfarin failure syndromes while in the therapeutic range are uncommon and occur ~1-2% of patients per year. They are less likely due to thrombophilic conditions and more due to highly inflammatory or thrombogenic conditions such as cancer or anti phospholipid syndrome. There are new oral anticoagulants such as rivaroxaban and dabigatran that are FDA approved for VTE and do not require monitoring.
Yes it can occur . It is very unlikely to have a DVT when on warfarin at a therapeutic level inr 2.5 , but it does happen. Usually there are multiple risk factor involved : such as factor v , plus recent DVT , plus some other risk factors, or possibly just being homozygous [ a mutation in both alleles of factor v leiden]. So it is rare but can happen . I hope this helps.
Warfarin. Yes, but only if the therapeutic inr range is not ideal. At 2.5 you are perfect and the risk for clots diminishes at this level.

Related Questions

My mother has Factor V Leiden; Eliquis twice daily. Shes had multiple DVTs and clots in her lungs. Does she need to stop taking to pull a tooth?

No. greater risk of blood clots and pulmonary emboli than bleeding from a tooth, check with her hematologist and dentist but the greater risk is stopping the Eliquis just like if she needed a colonoscopy , don't stop it due to small risk of g.i. bleed ,worry about the heart attack or pulmonary emboli and death from a blood clot. and other tests use this logic. Read more...

Pos for 2 copies of G20210A. Parents tested neg. How is that possible? I have 1 copy of Factor V Leiden & Dad has 2 copies. Mom has a blood clot in leg.

Prob error in test. May be test error in you or Mom. Likely that Dad has transmitted F V Leiden to you as expected. Either he or your Mom likely also has F II (20210A) mutation- guess would be your mom due to her blood clot. Possible you are a new mutation for 20210A but very very rare and unlikely. Other possibility is non-paternity or non-maternity. Read more...
Interesting. For you to be homozygous(having two abnormal copies) for the prothrombin 20210 gene then both of your biologic parents had to have at least one copy of the abnormal gene. You inherit one copy of the prothrombin gene from your mother and the other from your father. So while your biologic parents may not be "homozygous" they must at least be "heterozygous" for the 20210 gene. . Read more...

My son has factor v leiden, He has a blood clot in his leg and the doctors are talking about doing surgery. What kind of surgery would they do?

Blood clots -surgery. There are several possibilities here for what they may be talking about, depending on the situation. In rare instances, a blood clot may need to actually be removed. Again, this is quite uncommon but not unheard of. They may also be talking about putting a filter in one of the big blood vessels going back to his heart, so that if a bit of the clot breaks of it can't get to his heart of brain. ASK! Read more...

I've 1 copy of Factor V Leiden & have a blood clot in my femoral artery as a result of an angiogram, with no flow. Will the clot eventually break off?

Not likely. The femoral artery that closed following a procedure is unlikely to open. What usually happens is small arteries called collaterals open up to preserve the circulation in the lower extreme ties. It is often inadequate and most often will require opening the artery by balloon angioplasty/stent or by surgery. This is often done as soon as it is recognized that the femoral artery has closed . Read more...
Unlikely. If there is "no flow" in the femoral artery, then presumably there are collateral ("bypass") vessels bringing blood to your leg if you are in a stable condition. Most commonly these vessel closures become permanent, with the collaterals growing over time. The clot solidifies and becomes fibrous material that is not fragile or prone to fragmentation. Read more...

What do you suggest if my oldest son has factor v leiden, he has a blood clot in his leg an the doctors are talking about doing surger?

What surgery ? Surgery is not a very common solution to a blood clot in the leg. What exactly are they proposing to do and what are your concerns about that? Usually blood thinners are the answer, but occasionally there could be a recommendation for an IVC filter to prevent the clot from going to the lungs. Please ask what and re-submit question with more details... Read more...

Should I be concerned if my oldest son has factor v leiden, he has a blood clot in his leg an the doctors are talking about doing surger?

Risk of blood clots. People who have one factor v leiden gene are at about 5 times greater risk for clot formation and those with two genes are at 50 times greater risk. Please discuss the issue with your doctors. If you have daughters, consult your doctor before they take birth control pills. Read more...