Many options. First, find out what's causing the cushing's syndrome. If it's due to overuse of steroids, cut down on the dose. If it's due to a tumor, surgery is the best treatment.Tumor in the pituitary can be removed by neurosurgeons, tumors in the adrenal, pancreas, lung can be removed by surgeons. Radiation therapy is used if surgery is not complete. Last but not least, medications can be used.