2 doctors weighed in:

All lupus blood tests negative but have all the symptoms. Pcp agrees. Seeing lupus doctor in 1 month. Is it possible to have lupus with negative labs?

2 doctors weighed in
Dr. Ronald Krauser
Internal Medicine - Rheumatology
1 doctor agrees

In brief: Rarely

There is a rare individual who may have ANA negative lupus.
However, if the ANA is negative, the ssa is often positive. I have personally not seen a true ANA negative lupus patient in years.

In brief: Rarely

There is a rare individual who may have ANA negative lupus.
However, if the ANA is negative, the ssa is often positive. I have personally not seen a true ANA negative lupus patient in years.
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