2 doctors weighed in:

Msg makes me have panic attacks and burning pain all over with extreme irritability. Is this caused by glutamate receptor problem or channelopathies?

2 doctors weighed in
Dr. Bahman Omrani
Pain Management
1 doctor agrees

In brief: MSG symptom complex

The proposed mechanism is though to involve exaggerated sensitivity to msg which is metabolized to glutamate, a dominant excitatory Amino Acid neurotransmitter.
Msg is a normal constituent of food protein and rarely causes symptoms when excess amount are not added to food. The complex has to do with upregulation of normal receptors as opposed to a channelopathy or a glutamate receptor problem.

In brief: MSG symptom complex

The proposed mechanism is though to involve exaggerated sensitivity to msg which is metabolized to glutamate, a dominant excitatory Amino Acid neurotransmitter.
Msg is a normal constituent of food protein and rarely causes symptoms when excess amount are not added to food. The complex has to do with upregulation of normal receptors as opposed to a channelopathy or a glutamate receptor problem.
Dr. Bahman Omrani
Dr. Bahman Omrani
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