Type and severity. Treatment depends on the type of vasulitis which are many, the severity and response which varies. Steroids are the mainstay for many different types. Drugs such as methotrexate, azathioprine, Cyclosporine and Cyclophosphamide are some of the agents used. Surgery and stents may be needed in select patients to restore blood flow to vital organs. Vascular and rheumatologist consult recommended.