My allergist told me there is almost no way I am allergic to benadryl (diphenhydramine). Why do I get a few hives 20 minutes after taking it, then? I take dye free.

It is possible. Your allergist is correct in that allergy to Benadryl (diphenhydramine) is very rare. However, it can occur, especially if you have frequently used creams or lotions containing Benadryl (diphenhydramine) on your skin. If you are still concerned about it, talk with your allergist about performing skin testing to benadryl (diphenhydramine). Alternatively, he may perform a "challenge, " in which you are given a few increasing doses to see if you react.

Related Questions