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Why does topamax (topiramate) cause tingling in hands and feet?

1 doctor weighed in

In brief: Mechanism of action

The drug does affect numerous neurotransmitters and certainly in some affects acid-base balance (adverse event is metabolic acidosis).
Any of these mechanisms could promote paresthesias. However, patients have mitigated this by ingestion of bananas or dried apricots, sources of potassium plus other ingredients.

In brief: Mechanism of action

The drug does affect numerous neurotransmitters and certainly in some affects acid-base balance (adverse event is metabolic acidosis).
Any of these mechanisms could promote paresthesias. However, patients have mitigated this by ingestion of bananas or dried apricots, sources of potassium plus other ingredients.
Dr. Bennett Machanic
Dr. Bennett Machanic
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Dr. Bennett Machanic
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