Unusual in US Europe. Primary liver cancer is relatively unusual in most of the world unless the patient has chronic hepatitis b or c. In parts of asia, primary liver cancer is more common and may be related to other infections. Cancer from other sites that metastasizes to the liver (especially colon and lung) is relatively common.
Common worldwide. Liver cancer in men is the 5th most frequently diagnosed cancer worldwide, and is the 2nd leading cause of cancer-related death in the world. In the United States, liver cancer is not very common, however the incidence increases along with the increase incidence of hep b and c infection. Also related to choric cirrhosis due to alcohol consumption and fatty liver disease.