Severe headache after air travel. What can I do or take to relieve this?

Pseudoephedrine, AND. Momzbma, if you have headaches after air travel, it is possible that you are not equalizing pressure in your sinuses well. Although sometimes Pseudoephedrine or phenylephrine tablets can help with this, i would recommend discussing it with your family doctor and possibly seeing a ear/nose/throat (ENT) physician for further evaluation.