Cyclosporine & hives. Cyclosporine is being studied as possible tx for chronic hives. "this immune system suppressant can help with symptoms, but can cause serious side effects & must be monitored carefully. The fda warns that taking Cyclosporine (gengraf, neoral, (cyclosporine) others) puts you at greater risk of opportunistic infections, such as the activation of a previous infection." —> see comment for source.