3 doctors weighed in:

What is the standard dose of methotrexate for treating psoarisis?

3 doctors weighed in
Dr. Ronald Krauser
Internal Medicine - Rheumatology
1 doctor agrees

In brief: 15-25 mg weekly

There is no one standard dose.
I have found that a range of 15-25 mg weekly works best for most of my psoriasis patients.

In brief: 15-25 mg weekly

There is no one standard dose.
I have found that a range of 15-25 mg weekly works best for most of my psoriasis patients.
Dr. Ronald Krauser
Dr. Ronald Krauser
Thank
Dr. Thomas Namey
Internal Medicine - Rheumatology

In brief: 15-25 mg /week!

I firmly believe Methotrexate should be given by the subcutaneous route once weekly.
You bypass the gut, cut down the 300 x first pass overload though the liver, and have far fewer GI issues. Also, since people absorb between 40-90% of mtx by the oral route, but absorb 100% by the s.C. Route, it is difficult to argue for oral mtx. I would not take it orally myself. The dose is based on response!

In brief: 15-25 mg /week!

I firmly believe Methotrexate should be given by the subcutaneous route once weekly.
You bypass the gut, cut down the 300 x first pass overload though the liver, and have far fewer GI issues. Also, since people absorb between 40-90% of mtx by the oral route, but absorb 100% by the s.C. Route, it is difficult to argue for oral mtx. I would not take it orally myself. The dose is based on response!
Dr. Thomas Namey
Dr. Thomas Namey
Thank
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