Is a constant IgE level of 200+ iu/ml something that could potentially cause severe symptoms that I have, or is it something that should be neglected?

Elevated IgE. An elevated ige level can be seen in many disorders including allergic disorders (eczema, asthma), inflammatory disorders and even in some immune deficiency disorders. The level by itself doesn't mean as much, but it alerts the physician to assess for an underlying cause.