8 doctors weighed in:
As we know that fibro is due to abnormalities in the levels of chemicals in the brain but how could treatment restore the normal balance of chemicals?
8 doctors weighed in

Dr. Kenneth Choquette
Pain Management
4 doctors agree
In brief: Sensitization
Central sensitization is the process of the CNS nerve receptors becoming hyper-sensitive to stimulation whereas normal touch and movement becomes painful.
This is one of the working possibilities behind fm. The issue remains that little is none as to how to diagnose and how to treat. This symdrome is diagnosed too often and too early, with many complaints explained by other pathology.

In brief: Sensitization
Central sensitization is the process of the CNS nerve receptors becoming hyper-sensitive to stimulation whereas normal touch and movement becomes painful.
This is one of the working possibilities behind fm. The issue remains that little is none as to how to diagnose and how to treat. This symdrome is diagnosed too often and too early, with many complaints explained by other pathology.
Dr. Kenneth Choquette
Dr. Kenneth Choquette
Thank
Dr. Gregory Hines
Family Medicine
4 doctors agree
In brief: Not sure at all
I would not agree with your premise.
Nobody knows what causes fibromyalgia, thus it has been difficult to treat. As we learn more about it, then treatments have improved somewhat, but the best thing for it continues to be exercise, regular sleep, and plenty of hydration.

In brief: Not sure at all
I would not agree with your premise.
Nobody knows what causes fibromyalgia, thus it has been difficult to treat. As we learn more about it, then treatments have improved somewhat, but the best thing for it continues to be exercise, regular sleep, and plenty of hydration.
Dr. Gregory Hines
Dr. Gregory Hines
Thank
1 comment
Dr. John Goldman
We have data to suggest that in some patients there is increase in nerve activity in some areas of the brain, whihc was not see in the control population. This may apply to some people and there may be other associatons in others. I agree with Dr Hines and would encourage exercise. The pain is in the muscles. Quality sleep may need to be evaluated as well as stress and psychological issues.
Dr. Chad Boomershine
Internal Medicine - Rheumatology
1 doctor agrees
In brief: Medications work
Fibro patients have lower levels of some brain chemicals (eg, serotonin and norepinephrine) and higher levels of others (eg, glutamate, substance p).
These abnormal brain chemical levels cause the symptoms of fibro. Medications like Cymbalta and savella (milnacipran) work by increasing brain levels of serotonin and norepinephrine. Medicines like Lyrica treat symptoms by decreasing glutamate and substance p.

In brief: Medications work
Fibro patients have lower levels of some brain chemicals (eg, serotonin and norepinephrine) and higher levels of others (eg, glutamate, substance p).
These abnormal brain chemical levels cause the symptoms of fibro. Medications like Cymbalta and savella (milnacipran) work by increasing brain levels of serotonin and norepinephrine. Medicines like Lyrica treat symptoms by decreasing glutamate and substance p.
Dr. Chad Boomershine
Dr. Chad Boomershine
Thank
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