7 doctors weighed in:

Does taking prozac, (fluoxetine) lamictal, or ibuprofen increase chances of bruising? My friend is getting a lot more bruises on her legs than ever before.

7 doctors weighed in
Dr. Luis Villaplana
Internal Medicine
5 doctors agree

In brief: Meds n bruising

Of those 3, lam octal and Ibuprofen can.
If i had to pick one, it would be ibuprofen. Depending on dose and how long you've been on lamictal, i would definitely discuss it with your doctor. Simple labs can tell if Lamictal is affecting your blood counts and increasing your risk for bruising and or potentially bleeding.

In brief: Meds n bruising

Of those 3, lam octal and Ibuprofen can.
If i had to pick one, it would be ibuprofen. Depending on dose and how long you've been on lamictal, i would definitely discuss it with your doctor. Simple labs can tell if Lamictal is affecting your blood counts and increasing your risk for bruising and or potentially bleeding.
Dr. Luis Villaplana
Dr. Luis Villaplana
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Dr. Colin Kerr
Family Medicine
2 doctors agree

In brief: Bruising

Very possibly. Ibuprofen, like aspirin, interferes with normal blood platelet cell function and can lead to increased bruising.
Prozac (fluoxetine) is also associated with a much more mild bleeding effect. My suggestion would be to stop the Ibuprofen for several weeks and see if it improves.

In brief: Bruising

Very possibly. Ibuprofen, like aspirin, interferes with normal blood platelet cell function and can lead to increased bruising.
Prozac (fluoxetine) is also associated with a much more mild bleeding effect. My suggestion would be to stop the Ibuprofen for several weeks and see if it improves.
Dr. Colin Kerr
Dr. Colin Kerr
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Dr. Dheeraj Raina
Psychiatry

In brief: Yes.

Ibuprofen is probably most likely to cause this s/e by preventing platelets (clot-promoting blood cells) from clumping together, though Prozac (fluoxetine) can also cause this s/e in a similar way.
Lamictal can rarely cause this s/e by a different and more serious mechanism, i.e. Reduction in number of platelets. Your friend needs to urgently speak to his/her doctor about this. Good luck to both of you.

In brief: Yes.

Ibuprofen is probably most likely to cause this s/e by preventing platelets (clot-promoting blood cells) from clumping together, though Prozac (fluoxetine) can also cause this s/e in a similar way.
Lamictal can rarely cause this s/e by a different and more serious mechanism, i.e. Reduction in number of platelets. Your friend needs to urgently speak to his/her doctor about this. Good luck to both of you.
Dr. Dheeraj Raina
Dr. Dheeraj Raina
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