Is it safe to drink alcohol while on dicloxacillin?

Relatively. Alcohol and Dicloxacillin do not have any severe interactions, however, you should not drink while you are on an antibiotics. Alcohol consumption will temporarily lower your immune system making it harder for the antibiotic to heal your infection as well as lowering the drugs efficacy. If you are sick enough to be on an antibiotics, you should not drink alcohol.