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My 7 year old daughter has been diagnosed with cpp and her doctor wants to start her on lupron (leuprolide) depot ped 7.5mg monthly. How safe is this medication?

5 doctors weighed in
Dr. George Klauber
Pediatrics - Urology
4 doctors agree

In brief: Safe up to 55 lbs wt

Central precocious puberty requires both early development of both pubic hair + breast development.
Should be safe for girls weighing up to 55 lbs. Should be given regularly every 28 days. Consider 2nd opinion if daughter is older than age-8-years.

In brief: Safe up to 55 lbs wt

Central precocious puberty requires both early development of both pubic hair + breast development.
Should be safe for girls weighing up to 55 lbs. Should be given regularly every 28 days. Consider 2nd opinion if daughter is older than age-8-years.
Dr. George Klauber
Dr. George Klauber
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1 comment
Dr. George Klauber
Dose of Lupron for her should probably be 10.0mg every 28 days. She will probably stop grwing any taller than 2'' after going through puberty. Lupron will both temporally arrest her CPP, but allow her to grow taller than she would otherwise. Children with CPP are usually taller than their peers, but later end up much shorter because growing ends of bone tend to fuse + growth stops
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