Will diarrhea stop me from going on my vacation?

Have a nice time. If your diarrhea is mild, of brief duration, caused by a number of viruses, food poisoning, or a self-limited low-grade infection then go have a nice time on your trip. However, if your diarrhea is profuse, wakes you from sleep, is associated with fever and/or abdominal pain/tenderness, bleeding, or is persistent then leaving familiar local medical resources is not recommended--go get checked.