2 doctors weighed in:

In celiac disease how much time does it take for the histopathoological changes to normalise once gluten free diet is started?

2 doctors weighed in
Dr. Amy Deeken
Pathology
1 doctor agrees

In brief: Usually

About 6 months. However, every person' body heals differently.
It is reported about that it can take up to 2 years to normalize. But, if there is any exposure to gluten, the changes may still be persistent. It is helpful to monitor serum ttg antibody levels, once they normalize, rebiopsy on about 6 months. Repeat biopsies should continue to be read in the same lab so slides can be compared.

In brief: Usually

About 6 months. However, every person' body heals differently.
It is reported about that it can take up to 2 years to normalize. But, if there is any exposure to gluten, the changes may still be persistent. It is helpful to monitor serum ttg antibody levels, once they normalize, rebiopsy on about 6 months. Repeat biopsies should continue to be read in the same lab so slides can be compared.
Dr. Amy Deeken
Dr. Amy Deeken
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