I have chronic RLS after 3yrs on mirapex (pramipexole) it now causes symptoms to worsen! Also on codeine sulfate. What's next? Thought i'd found the relief

Troublesome! . Rls is very troublesome. All the meds we use show tolerance over time. You can google the laundry list of meds we use (sinemet, klonopin, neurontin, mirapex, (pramipexole) etc.) but your best bet is to sit down with a sleep specialist in your area. He/she can guide next med selection. Btw, occasionally 400 mg of magnesium helps before bedtime. Cheap, too. Best of luck!