Can I take epherine when taking levothyroxine?

Do you mean . Ephedrine (ephedrine (ephedrine sulfate) sulfate)? If so, there are very few modern indications for ephedrine (ephedrine sulfate). Why are you taking it, and has it been recommended by your doctor? It can interact with T4 (levothyroxine) depending upon the dose and levels of both drugs. There are better and safer asthma meds if that's why you're on itl.