My friend has a nodule on the right upper lobe & a hypodense lesion on her right thyroid lobe, so does that mean if she has cancer it is spreading?

No. Hypodense lesion is an ultrasound term that describes the appearance of a thyroid nodule. Most thyroid nodules are hypodense, and most of these nodules are benign. If it is over 1 cm in size, fine needle biopsy of the nodule should be considered to determine if it is benign or not.