What might I do to get relief from muscle spasms in my legs (charlie horses)?

Muscle spasms. There are not always easy solutions, but first be certain you are well hydrated and eat good sources for minerals. This can sometimes mean a problem with calcium but that should be assessed by labs. There are other labs that can be done. Also ok to try magnesium malate in a dose of 200 to 500 mg per day, watching for diarrhea (means too much).