Will unexplained weight loss kill me if I don't get treatment?

Possible. Hi, you need to have a full history and physical exam, also an eval of the stresses in your life. You need to have a diagnosis, unexplained weight loss is a symptom not really a diagnosis. Yes, its true that unexplained wt. Loss could be a sign of a lethal disease such as some types of cancer.But, an experienced physician may find that your weight loss has an explanation and is treatable/curable.