14 doctors weighed in:
What meds are good for cholestasis of pregnancy?I had it once and don't want to experience it again.
14 doctors weighed in

Mike Moore
Family Medicine
11 doctors agree
In brief: UCDA
Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp).
We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy.

In brief: UCDA
Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp).
We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy.
Mike Moore
Mike Moore
Answer assisted by Mike Moore, Medical Student
Thank
1 comment
Dr. Peter Corrado
very interesting, I did not know this. Thanks P. Corrado
Dr. Byron Hapner
Obstetrics & Gynecology
2 doctors agree
In brief: Cholestyramine
Urso (udca) is one medication; another is cholestyramine.
To summarize, you should suspect cholestasis of pregnancy when there is intense itching and no corresponding rash on the skin. Lab tests should be ordered to confirm abnormal liver function. Consequences of cholestasis include fetal death, premature labor and postpartum hemorrhage--all requiring close monitoring.

In brief: Cholestyramine
Urso (udca) is one medication; another is cholestyramine.
To summarize, you should suspect cholestasis of pregnancy when there is intense itching and no corresponding rash on the skin. Lab tests should be ordered to confirm abnormal liver function. Consequences of cholestasis include fetal death, premature labor and postpartum hemorrhage--all requiring close monitoring.
Dr. Byron Hapner
Dr. Byron Hapner
Thank
Get help from a real doctor now
Dr. Dennis Higginbotham
Board Certified, Obstetrics & Gynecology
26 years in practice
49M people helped
Continue
107,000 doctors available
Read more answers from doctors