4 doctors weighed in:

Can spironolactone cause melasma or make it worse?

4 doctors weighed in
Dr. David Sneid
Internal Medicine - Endocrinology
3 doctors agree

In brief: Not known

Melasma can worsen due to estrogen, progesterone, sun exposure, etc.
Spironolactone can lower testosterone, so in theory it could increase estrogen slightly, but have never seen it described as causing or worsening melasma.

In brief: Not known

Melasma can worsen due to estrogen, progesterone, sun exposure, etc.
Spironolactone can lower testosterone, so in theory it could increase estrogen slightly, but have never seen it described as causing or worsening melasma.
Dr. David Sneid
Dr. David Sneid
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