My hands wrinkle and hurt only after a few minutes being exposed to the water. It's just happen recently. Why is this occur?

AquagenicKeratoderma. Aquagenic keratoderma is a condition which causes the symptoms you describe. Keeping the hands as dry as possible is helpful. Prescriptions such a drysol can help. Consult a dermatologist to see if this is the cause of your symptoms.