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Does taking Zofran (ondansetron) make stomach virus last longer?

1 doctor weighed in
Dr. Kathleen Mullane
Internal Medicine

In brief: More's not better

Zofran (ondansetron) may slow the transit time in the gut and rarely the bowels can stop moving.
Therefore potential to prolong the period of time in wh/a virus is in contact w/the gut. In a study in children w/vomiting gastroenteritis who took zofran (ondansetron) x 48 hrs, return to the er w/diarrhea was higher in the kids w/zofran (ondansetron). Another study gave 1 dose & the er return was less w/zofran (ondansetron) but kids had more diarrhea.

In brief: More's not better

Zofran (ondansetron) may slow the transit time in the gut and rarely the bowels can stop moving.
Therefore potential to prolong the period of time in wh/a virus is in contact w/the gut. In a study in children w/vomiting gastroenteritis who took zofran (ondansetron) x 48 hrs, return to the er w/diarrhea was higher in the kids w/zofran (ondansetron). Another study gave 1 dose & the er return was less w/zofran (ondansetron) but kids had more diarrhea.
Dr. Kathleen Mullane
Dr. Kathleen Mullane
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