8 doctors weighed in:
Can someone have MS and not have any leisons ?
8 doctors weighed in

Dr. Gael Yonnet
Neurology
4 doctors agree
In brief: No
In fact, the mcdonald criteria for the diagnosis of multiple sclerosis requires dissemination of lesions both in time and space.
Without any lesions, the diagnosis can not be made. So, strickly speaking, the absence of lesions is not compatible with a diagnosis of ms.

In brief: No
In fact, the mcdonald criteria for the diagnosis of multiple sclerosis requires dissemination of lesions both in time and space.
Without any lesions, the diagnosis can not be made. So, strickly speaking, the absence of lesions is not compatible with a diagnosis of ms.
Dr. Gael Yonnet
Dr. Gael Yonnet
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Dr. Olav Jaren
Neurology
1 doctor agrees
In brief: Rare type of MS
It is possible to have primary progressive MS and have no lesions.
The clinical course shows no relapses though, just a steady decline over many years. It behaves more like a degenerative disease, and it does not respond to MS medical treatments. For the most part, if the MRI studies are normal, MS is probably not the right diagnosis.

In brief: Rare type of MS
It is possible to have primary progressive MS and have no lesions.
The clinical course shows no relapses though, just a steady decline over many years. It behaves more like a degenerative disease, and it does not respond to MS medical treatments. For the most part, if the MRI studies are normal, MS is probably not the right diagnosis.
Dr. Olav Jaren
Dr. Olav Jaren
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Dr. Colin Kerr
Family Medicine
In brief: MS
When you say "not have any lesions", do you mean a patient has symptoms (which represent neurological lesions) but has no lesions that show up on an mri.
This is common in the early stages of ms; lesions are likely to show over time. There would be no way to diagnose MS is there were no actual symptoms (representing neurological lesions).

In brief: MS
When you say "not have any lesions", do you mean a patient has symptoms (which represent neurological lesions) but has no lesions that show up on an mri.
This is common in the early stages of ms; lesions are likely to show over time. There would be no way to diagnose MS is there were no actual symptoms (representing neurological lesions).
Dr. Colin Kerr
Dr. Colin Kerr
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